54 year old man with blood in urine and abdominal discomfort for the past 2 days. PMH includes HTN. PE is unremarkable. CT abdomen shows bilaterally enlarged kidneys with multiple cysts. Mode of inheritance of this patients condition?

The 54 year-old patient likely has Polycystic Kidney Disease (PKD), a genetic disorder that can be inherited in an autosomal dominant or recessive manner, with the former being more common in adults.

Explanation:

The described condition of the 54 year-old man shows symptoms quite characteristic of Polycystic Kidney Disease (PKD), a genetic disorder that causes multiple cysts to form in the kidneys. In this context, HTN refers to hypertension, a common symptom associated with PKD.

The mode of inheritance of this condition can either be autosomal dominant polycystic kidney disease (ADPKD) or autosomal recessive polycystic kidney disease (ARPKD). The former is more common, particularly in adults, and is usually associated with mutations in the PKD1 or PKD2 genes. An individual with an affected parent has a 50% chance of inheriting this condition.

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