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Medication order: Fluconazole 12 mg/kg IV on day 1.

Supply on hand: Fluconazole 2 mg/mL.

Patient's weight: 157 lbs.

Calculate the dosage to give in mL: _______ mL.

Answer :

Final answer:

To determine the fluconazole IV dosage for a 157 lb patient, convert the patient's weight to kg, calculate the total mg dose needed, and divide by the mg/mL concentration of the drug solution to get 427.29 mL.

Explanation:

To calculate the fluconazole dose in mL that should be administered IV on day 1, follow these steps:

  1. First, convert the patient's weight from pounds to kilograms. 157 lbs × 1 kg/2.2046 lbs = 71.215 kg (rounded to three decimal places).
  2. Next, calculate the total dosage required in mg using the prescribed dosage of 12 mg/kg. The total dosage needed is 71.215 kg × 12 mg/kg = 854.58 mg (rounded to two decimal places).
  3. Finally, determine the volume of fluconazole solution needed by dividing the total dosage in mg by the concentration of the fluconazole supply. In this case, 854.58 mg ÷ 2 mg/mL = 427.29 mL (rounded to two decimal places).

Therefore, the nurse should administer 427.29 mL of fluconazole 2 mg/mL IV on day 1.