Answer :
Final answer:
To determine the fluconazole IV dosage for a 157 lb patient, convert the patient's weight to kg, calculate the total mg dose needed, and divide by the mg/mL concentration of the drug solution to get 427.29 mL.
Explanation:
To calculate the fluconazole dose in mL that should be administered IV on day 1, follow these steps:
- First, convert the patient's weight from pounds to kilograms. 157 lbs × 1 kg/2.2046 lbs = 71.215 kg (rounded to three decimal places).
- Next, calculate the total dosage required in mg using the prescribed dosage of 12 mg/kg. The total dosage needed is 71.215 kg × 12 mg/kg = 854.58 mg (rounded to two decimal places).
- Finally, determine the volume of fluconazole solution needed by dividing the total dosage in mg by the concentration of the fluconazole supply. In this case, 854.58 mg ÷ 2 mg/mL = 427.29 mL (rounded to two decimal places).
Therefore, the nurse should administer 427.29 mL of fluconazole 2 mg/mL IV on day 1.