High School

You wonder whether green tea lowers cholesterol.

(a) To research the claim that green tea lowers LDL (so-called bad) cholesterol, you ask a random sample of individuals to divulge whether they are regular green tea users or not. You also obtain their LDL cholesterol levels. Finally, you compare the LDL cholesterol levels of the green tea drinkers to those of the non-green tea drinkers. Explain why this is an observational study.

(b) Name some lurking variables that might exist in the study.

(c) Suppose, instead of surveying individuals regarding their tea-drinking habits, you decide to conduct a designed experiment. You identify 120 volunteers to participate in the study and decide on three levels of the treatment: a placebo, one cup of green tea daily, and two cups of green tea daily. The experiment is to run for one year. The response variable will be the change in LDL cholesterol for each subject from the beginning of the study to the end. What type of experimental design is this?

(d) Explain how you would use blinding in this experiment.

(e) What is the factor? Is it qualitative or quantitative?

(f) What factors might you attempt to control in this experiment?

(g) Explain how to use randomization in this experiment. How does randomization neutralize those variables that are not controlled?

(h) Suppose you assigned 40 subjects to each of the three treatment groups. In addition, you decided to control the variable exercise by having each subject perform 150 minutes of cardiovascular exercise each week by walking on a treadmill. However, the 40 subjects in the placebo group decided they did not want to walk on the treadmill and skipped the weekly exercise. Explain how exercise is now a confounding variable.

Answer :

Final answer:

An observational study is conducted to observe and collect data without manipulating variables. Lurking variables like age, diet, exercise, genetics, and overall health might exist in the study. The experimental design mentioned is a randomized controlled experiment. Blinding can be used by using identical-looking placebos and green tea. The factor in this experiment is the level of green tea consumption, which is qualitative. Factors like age, diet, exercise, and overall health might be controlled. Randomization is used to distribute variables equally among groups. Exercise becomes a confounding variable when it is not controlled for in the placebo group.

Explanation:

An observational study is a type of study where the researcher observes and collects data without intervening or manipulating any variables. In this case, the researcher is observing the LDL cholesterol levels of green tea drinkers and non-green tea drinkers to investigate whether green tea lowers LDL cholesterol. This study is observational because the researcher is not assigning participants to different groups or manipulating their tea-drinking habits. Instead, the researcher is simply observing and comparing the LDL cholesterol levels of the two groups.

Some lurking variables that might exist in this study include age, diet, exercise, genetics, and overall health. These variables are not directly measured or controlled but may have an effect on the outcome. For example, individuals who drink green tea regularly might also have healthier diets or engage in more physical activity, which could contribute to lower LDL cholesterol levels.

The experimental design mentioned in the question is a randomized controlled experiment. The researcher identifies 120 volunteers and assigns them to three treatment groups: placebo, one cup of green tea daily, and two cups of green tea daily. The experiment will run for one year, and the response variable will be the change in LDL cholesterol for each subject from the beginning to the end of the study.

To use blinding in this experiment, the researcher can use identical-looking placebos for the control group and green tea for the treatment groups. This way, the participants and researchers will be unaware of the treatment they are receiving or administering, minimizing bias.

The factor in this experiment is the level of green tea consumption, which is a qualitative factor with three levels: placebo, one cup of green tea daily, and two cups of green tea daily.

In this experiment, the researcher might attempt to control factors such as age, diet, exercise, and overall health. By controlling these factors, the researcher can minimize their potential influence on the LDL cholesterol levels and isolate the effect of green tea consumption.

Randomization is used in this experiment by randomly assigning the participants to the treatment groups. Randomization helps neutralize variables that are not controlled by ensuring that they are equally distributed among the groups. This way, any differences observed in the LDL cholesterol levels can be attributed to the different levels of green tea consumption rather than other variables.

Exercise becomes a confounding variable in this experiment because it is not controlled for in the placebo group. The 40 subjects in the placebo group who decided not to walk on the treadmill and skipped the weekly exercise introduce a potential bias in the results. The lack of exercise in the placebo group could affect their LDL cholesterol levels, making it difficult to isolate the effect of green tea consumption on cholesterol.

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