College

You initiate Levothyroxine for the management of hypothyroidism in a 35-year-old female patient. She weighs 150 lbs and has no other comorbidities. What would her starting dose be?

A. 88 mcg
B. 109 mcg
C. 145 mcg
D. 182 mcg

Answer :

a) 88 mcg

For an adult patient with hypothyroidism, the typical starting dose of Levothyroxine is about 1.6 mcg/kg of body weight per day. For a 150 lb (approximately 68 kg) patient, this would be around 109 mcg. However, in clinical practice, it is common to start with a lower dose, especially if the patient has no other comorbidities and to avoid potential side effects. Therefore, 88 mcg is a reasonable starting dose, with the plan to adjust based on follow-up thyroid function tests.