Answer :
Balanced equation for Grignard reaction:
2-bromopropane + Mg → MgBr₂ + CH₃CHBrMgBr (Grignard reagent)
Synthesis of 1-(4-methoxyphenyl)-2-methylpropan-1-ol from Grignard reagent and 4-methoxybenzaldehyde:
CH₃CHBrMgBr + 4-methoxybenzaldehyde → 1-(4-methoxyphenyl)-2-methylpropan-1-ol
The Grignard reaction involves the reaction of an alkyl or aryl halide with magnesium in the presence of anhydrous ether to form a Grignard reagent. In this case, 2-bromopropane reacts with magnesium to form the Grignard reagent CH₃CHBrMgBr.
The Grignard reagent can then react with an aldehyde or ketone to form an alcohol. In this case, the Grignard reagent reacts with 4-methoxybenzaldehyde to form 1-(4-methoxyphenyl)-2-methylpropan-1-ol.
The reaction mechanism involves the attack of the Grignard reagent on the carbonyl group of the aldehyde, followed by protonation and elimination of the ether molecule to form the alcohol. Overall, the Grignard reaction is an important tool in organic synthesis for forming carbon-carbon bonds and creating complex organic molecules.
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