Answer :
Final answer:
Niosomes are avoided due to challenges with scaling-up, expensive preparation, and producing sterile products. Liposomes and niosomes can be effective for targeted drug delivery, but their design must be carefully optimized to ensure efficiency and minimize adverse effects.
Explanation:
The use of niosomes is not inherently problematic, but there are reasons why we sometimes choose not to use them. They can be complex in their development, due to challenges in scaling-up production, expensive preparation processes, and difficulty ensuring sterile products.
However, it is critical to recognize that various nanocarrier systems, including niosomes and liposomes, have shown significant potential in the field of targeted drug delivery.
Research has demonstrated successful encapsulation of cancer therapeutics and imaging agents alike, enhancing biocompatibility and stability when coated with appropriate polymers like hyaluronic acid, which can target specific tissues such as tumor sites.
Nanoscale carriers like liposomes have proven to be effective for delivering active substances in therapeutic applications and in the development of immunoadjuvants.
They have the potential to simultaneously deliver multiple types of anticancer drugs or combination of therapeutics and genetic materials.
Despite their potential benefits, factors like the nanoparticle size, shape, surface charge, and ligand density must be carefully optimized to ensure efficient targeting and to minimize possible adverse effects such as toxicity or unintended immune responses.
