Answer :
Final answer:
Clonal expansion of B cells involves their activation, replication, and differentiation into plasma or memory cells. They do not differentiate into T cells during this process. Thus, the correct answer is that B cells becoming T cells does not occur during clonal expansion.
Explanation:
Understanding Clonal Expansion of B Cells
During the immune response, B cells go through a process known as clonal expansion. This process is crucial for producing a sufficient number of cells that can fight off pathogens.
What Occurs During Clonal Expansion?
- The B cell becomes activated upon encountering its specific antigen.
- Once activated, the replicated cells differentiate into plasma cells or memory cells.
- Plasma cells then secrete antibodies that bind to the same antigen as the receptor on the original B cell.
- Activated B cells divide, replicating themselves to ensure a robust immune response.
What Does Not Occur?
Importantly, the clonal expansion process does not involve differentiation of B cells into T cells, as that is a separate pathway involving different cell types. Therefore, the answer to the question is that B cells do not become T cells during clonal expansion.
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