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What does not occur during clonal expansion of B cells?

A. Replicated cells differentiate into plasma cells or memory cells.
B. B cell becomes activated.
C. Plasma cells secrete antibodies that bind to the same antigen as the receptor on the original B cell.
D. Activated B cells divide, replicating themselves.

Answer :

Final answer:

Clonal expansion of B cells involves their activation, replication, and differentiation into plasma or memory cells. They do not differentiate into T cells during this process. Thus, the correct answer is that B cells becoming T cells does not occur during clonal expansion.


Explanation:

Understanding Clonal Expansion of B Cells

During the immune response, B cells go through a process known as clonal expansion. This process is crucial for producing a sufficient number of cells that can fight off pathogens.

What Occurs During Clonal Expansion?

  • The B cell becomes activated upon encountering its specific antigen.
  • Once activated, the replicated cells differentiate into plasma cells or memory cells.
  • Plasma cells then secrete antibodies that bind to the same antigen as the receptor on the original B cell.
  • Activated B cells divide, replicating themselves to ensure a robust immune response.

What Does Not Occur?

Importantly, the clonal expansion process does not involve differentiation of B cells into T cells, as that is a separate pathway involving different cell types. Therefore, the answer to the question is that B cells do not become T cells during clonal expansion.


Learn more about clonal expansion here:

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