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------------------------------------------------ **Purpose/Hypotheses:**

Compose an introduction that covers the topics from our lecture and other classes (e.g., 335) applicable to the experiment. Do not simply copy and paste the lecture notes; use your own words to create a logical introduction. End with a clear purpose statement and appropriate hypotheses.

**Results:**

Create a table for each condition (control and occlusion; each minute on separate lines).

For each of the following figures, draw vertical lines to identify/separate when occlusion started and stopped (dotted line) and when exercise started and stopped (solid line):

- Plot HR as a function of time (HR on the y-axis, time on the x-axis) for each condition.
- Plot SBP, DBP, and MAP as a function of time (Pressures on the y-axis, time on the x-axis) for each condition.

**Discussion:**

Were the results (effect of occlusion on the HR and BP responses during exercise and post-exercise) what you expected? For each result, explain using concepts from the notes why the result was or was not expected.

**Procedures:**

4. Have the subject practice contracting and releasing the hand dynamometer at 30% MVC (maximal voluntary contraction) with their dominant hand at a rate of 40 contractions per minute (time the contractions with a metronome, available online or via a phone app). Have the subject rest for a minute afterward.

5. For the control experiment, collect and record blood pressure and heart rate at the end of each minute. Be sure to start the automated wrist blood pressure cuff with sufficient time to get your measurement near the end of the minute.
a. Collect 3 minutes of exercising data at 40 contractions per minute, at a level of 30% MVC.
b. Collect 3 minutes of recovery data with no contractions.

6. For the occluded experiment, collect and record blood pressure and heart rate at the end of each minute using the same technique used in the control experiment.
a. Occlude the subject's dominant arm by inflating the blood pressure cuff to 150-180 mmHg (this may vary between subjects; keep the cuff higher than their SBP). Take a blood pressure and heart rate measurement shortly after occlusion is started; this will be the resting measurement.
b. Collect 3 minutes of exercising data at 40 contractions per minute at 30% MVC with the subject's arm still occluded.
c. Leave the subject's arm occluded for the first minute of recovery data (i.e., keeping the metabolites trapped in the arm, but with no more contractions).
d. Release the pressure in the blood pressure cuff immediately after collecting and recording the first minute of recovery. Continue to collect 2 more minutes of recovery data (i.e., metabolites are now being removed from the previously exercised arm).

Answer :

Final answer:

The experiment investigates the effect of occlusion on heart rate (HR) and blood pressure (BP) responses during exercise and post-exercise. Occlusion refers to the restriction of blood flow to a specific area, achieved by inflating a blood pressure cuff to a pressure higher than the subject's systolic blood pressure (SBP). The experiment involves two conditions: control and occlusion. The purpose of the experiment is to examine how occlusion affects HR and BP responses during exercise and post-exercise. The hypotheses could be that occlusion will result in higher HR and BP responses during exercise and delayed recovery post-exercise.

Explanation:

Introduction:

In this experiment, we are investigating the effect of occlusion on heart rate (HR) and blood pressure (BP) responses during exercise and post-exercise. Occlusion refers to the restriction of blood flow to a specific area, which can be achieved by inflating a blood pressure cuff to a pressure higher than the subject's systolic blood pressure (SBP). The experiment involves two conditions: control and occlusion.

Purpose and Hypotheses:

The purpose of this experiment is to examine how occlusion affects HR and BP responses during exercise and post-exercise. The hypotheses could be that occlusion will result in higher HR and BP responses during exercise and delayed recovery post-exercise.

Experimental Procedure:

In the control condition, the subject will perform hand contractions at 30% MVC for 3 minutes, followed by 3 minutes of rest. Blood pressure and heart rate measurements will be taken at the end of each minute.

In the occlusion condition, the subject's arm will be occluded by inflating a blood pressure cuff to a pressure higher than their SBP. A blood pressure and heart rate measurement will be taken shortly after occlusion is started, which will serve as the resting measurement. The subject will then perform hand contractions at 30% MVC for 3 minutes, followed by 1 minute of rest with the cuff still inflated, and 2 more minutes of rest after releasing the cuff pressure. Blood pressure and heart rate measurements will be taken at the end of each minute.

Results:

For each condition (control and occlusion), create tables and plots for HR, SBP, DBP, and MAP as a function of time. Plot HR as a function of time on the y-axis and time on the x-axis for each condition. Plot SBP, DBP, and MAP as a function of time on the y-axis and time on the x-axis for each condition.

Discussion:

Discuss whether the results (effect of occlusion on the HR and BP responses during exercise and post-exercise) were what you expected. For each result, explain using concepts from the notes why the result was or was not expected.

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