High School

If a chiral center is formed from Grignard addition, a mixture of enantiomers will be formed. The Grignard reagent can attack at either the top face or bottom face of the carbonyl to give an equal mixture of chiral products.

Which carbonyls will give an achiral product after a Grignard reaction with [tex]CH_3MgBr[/tex]?

Answer :

The carbonyls that will give an achiral product after a Grignard reaction with CH3MgBr are aldehydes and ketones.

Aldehydes and ketones do not have a chiral center. These have two identical groups attached to the carbonyl carbon.

For example, formaldehyde (CH2O) and acetone (CH3COCH3) will give achiral products after a Grignard reaction with CH3MgBr.

In contrast, carbonyls that have two different groups attached to the carbonyl carbon, such as propanal (CH3CH2CHO) and 2-butanone (CH3CH2COCH3), will give a mixture of enantiomers after a Grignard reaction with CH3MgBr.

This is because the Grignard reagent can attack at either the top face or bottom face of the carbonyl to give an equal mixture of chiral products.

In summary, carbonyls that do not have a chiral center will give an achiral product after a Grignard reaction with CH3MgBr, while carbonyls that have a chiral center will give a mixture of enantiomers.

To know more about Grignard reaction, refer here:

https://brainly.com/question/30546045#

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