Answer :
1. Classical pathway of activation. C3 combines with factors B, D, and P on the microbe surface. The correct match is C. 2. Respiratory tract. Location of the mucociliary escalator. The correct match is B.
In the classical pathway of complement activation, the immune system responds to the presence of antigens by producing antibodies. When an antibody binds to an antigen, it triggers a cascade of reactions. In this case, C3, one of the complement proteins, combines with factors B, D, and P on the surface of the microbe. This interaction leads to the activation of the complement system, resulting in the recruitment of other immune cells and the destruction of the pathogen.
The mucociliary escalator is a defense mechanism in the respiratory tract that helps to remove foreign particles and pathogens from the airways. It consists of a layer of mucus produced by the epithelial cells lining the respiratory tract. This mucus traps particles and pathogens, preventing them from reaching the lungs. The cilia on the surface of the epithelial cells then beat in a coordinated manner, moving the mucus and the trapped particles upward towards the throat, where they can be coughed out or swallowed. This mechanism plays a crucial role in maintaining the health of the respiratory system by preventing the entry of harmful substances into the lungs.
Learn more about epithelial cells here:
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