High School

What does PTT represent in the coagulation pathway?

A. Extrinsic pathway
B. Intrinsic pathway
C. Common pathway
D. Fibrinolysis pathway

Answer :

Final answer:

PTT represents the intrinsic pathway in the coagulation pathway, leading to the activation of the common pathway and resulting in blood clot formation.

Explanation:

PTT represents the intrinsic pathway in the coagulation pathway. The intrinsic pathway is initiated when factor XII (Hageman factor) contacts foreign materials, leading to a series of activations of clotting factors XI, IX, and VIII, which in turn activate factor X, setting the stage for the common pathway. The common pathway is the final coagulation pathway activated either by the intrinsic or the extrinsic pathway, resulting in the formation of a blood clot where prothrombin is converted to thrombin, and fibrinogen is then turned into fibrin forming the stable clot structure.