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------------------------------------------------ The phenomenon of RNA interference is mediated by:

Option 1: Ribonucleotide reductase
Option 2: Argonaute proteins and small interfering RNAs (siRNAs)
Option 3: DNA polymerase
Option 4: RNA polymerase

The phenomenon of RNA interference is mediated by argonaute proteins and small interfering RNAs (siRNAs). It involves the binding of siRNAs to complementary mRNA molecules, preventing protein synthesis. Option 2 is correct.

Explanation:

The phenomenon of RNA interference is mediated by Argonaute proteins and small interfering RNAs (siRNAs) (Option 2).

RNA interference (RNAi) is a natural regulatory mechanism that prevents mRNA molecules from guiding the synthesis of proteins. It involves the base pairing of short, single-stranded antisense RNA molecules (siRNAs) to complementary mRNA molecules, which inhibits protein synthesis. The siRNAs are bound to DICER and then to RNA-induced silencing complex (RISC), which cleaves the mRNA or inhibits translation. This mechanism is known as gene silencing.

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