The oncologist has prescribed Herceptin at 4 mg/kg IV infusion over the next 90 minutes to a client weighing 114 lbs. After reconstituting, you have a multi-dose solution containing 21 mg/mL. How many mL should the nurse administer to the client?

To administer the correct dose of Herceptin, the nurse needs to convert the client's weight to kilograms, calculate the total dosage in mg, and then determine the volume of the solution needed. For a client weighing 114 lbs, approximately 9.87 mL of the Herceptin solution should be administered.

Explanation:

The question involves calculating how many mL of Herceptin a nurse should administer to a client. First, we need to convert the client's weight from pounds to kilograms as the dosage is prescribed in mg/kg. The client weighs 114 lbs, which is approximately 51.82 kg (since 1 lb is equal to 0.453592 kg). The prescribed dose is 4 mg/kg, therefore the total dose required is 51.82 kg × 4 mg/kg = 207.28 mg. Given that the concentration of the prepared solution is 21 mg/mL, the volume of the solution required is calculated by dividing the total dose by the concentration: 207.28 mg ÷ 21 mg/mL = 9.87 mL. Hence, the nurse should administer approximately 9.87 mL of the Herceptin solution to the client.