High School

One of the most important uses for Grignard reagents is their addition to carbonyl compounds to give new carbon-carbon bonds. In this reaction, the carbon of the carbonyl compound is attacked by the nucleophilic carbon of the Grignard reagent, resulting in the formation of a new carbon-carbon bond. What is the role of Grignard reagents in this reaction?
1) Acting as a nucleophile
2) Acting as an electrophile
3) Acting as a catalyst
4) Acting as a solvent

Answer :

Grignard reagents act as nucleophiles when adding to carbonyl compounds, forming a new carbon-carbon bond and transforming the compound into different types of alcohols based on their structure. Thus option 1 is correct.

The role of Grignard reagents in their addition to carbonyl compounds is primarily acting as a nucleophile. This means that in the reaction, the nucleophilic carbon of the Grignard reagent attacks the electrophilic carbon of the carbonyl compound, ultimately forming a new carbon-carbon bond.

The nucleophilic attack leads to the addition across the carbonyl bond, converting carbonyl compounds like aldehydes and ketones into various types of alcohols, depending on the number of alkyl substituents present on the carbonyl carbon. Thus option 1 is correct.