Answer :
The nurse should infuse argatroban at a rate of approximately 42.41 ml/hr.
To calculate the infusion rate of argatroban in ml/hr, we need to convert the weight of the patient from pounds to kilograms and then use the ordered dose to determine the infusion rate. Here are the steps:
1. Convert patient weight from pounds to kilograms:
187 lbs * (1 kg / 2.2046 lbs) = 84.82 kg (rounded to two decimal places)
2. Calculate the total dose per minute:
2 mcg/kg/min * 84.82 kg = 169.64 mcg/min
3. Convert the total dose from micrograms to milligrams:
169.64 mcg/min * (1 mg / 1000 mcg) = 0.16964 mg/min
4. Determine the infusion rate in ml/hr:
Since the pharmacy provided argatroban in a concentration of 100 mg/250 ml, we can set up a proportion:
0.16964 mg/min * (250 ml / 100 mg) * (60 min / 1 hr) = 42.41 ml/hr (rounded to two decimal places)
Therefore, the nurse should infuse argatroban at a rate of approximately 42.41 ml/hr to provide the desired dose for JK.
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