Answer :
Final answer:
Huntington's disease is an inherited, neurodegenerative disorder causing the wasting away of nerve cells in the brain. Its mode of inheritance is autosomal dominant, meaning there's a 50 percent chance of passing it to each offspring if one parent has the disease. The disease is caused by a mutation in the gene encoding the huntingtin protein.
Explanation:
Huntington's disease is an inherited, progressive, neurodegenerative disorder causing the gradual wasting away of nerve cells in the brain. This leads to a range of physical, psychological, and cognitive symptoms, including involuntary spastic movement and difficulty initiating and controlling voluntary movement.
People who are heterozygous for the dominant Huntington allele (Hh) will inevitably develop the disease. However, the onset of symptoms usually occurs around middle age, typically after the afflicted individuals may have already passed the allele to their children. The mode of inheritance for Huntington's disease is autosomal dominant, meaning that if one parent has the disease, there is a 50 percent chance of passing it to each offspring.
The exact mechanism causing this progressive death of neurons remains under study, with current evidence suggesting that the disease is caused by a mutation in the gene that encodes the huntingtin protein, leading to the production of an abnormal protein.
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