High School

Given the biaryl compound below, select the two reactants that would give this product via a Suzuki coupling. Drag and drop the appropriately labeled reactants into the starting box. Pd (PPh,) heat, Na,CO, E F G A CIB D SnBu 3 MgBr o Previous Give Up & View Solution Check Answer 0 Next AExit

Answer :

The product shown in the structure can be generated from a Suzuki coupling reaction using the reactants Na2CO3, Pd(PPh3)4, SnBu3 and MgBr.

First, the palladium (Pd) catalyst is activated by the Na2CO3 under basic conditions, which then reacts with the organoboron compound SnBu3 to form a palladium-boron complex. This complex then reacts with the aryl halide, E, under mildly basic conditions and the reaction is accelerated by heating. The aryl halide is then replaced with the aryl Grignard, MgBr, which undergoes a transmetalation to give the desired product A.

In summary, the two reactants needed for the Suzuki coupling are Na2CO3, Pd(PPh3)4, SnBu3 and MgBr.

For more similar questions on heating,

brainly.com/question/21927103

#SPJ11.

Other Questions