College

Dopamine in the ventral tegmental area is associated with which pathway?

A) Mesolimbic pathway
B) Serotonergic pathway
C) GABAergic pathway
D) Nigrostriatal pathway

Answer :

Final answer:

Dopamine in the ventral tegmental area is associated with the mesolimbic pathway (A), which is crucial for reward, addiction, and the motivational aspects of behaviors.

Explanation:

Dopamine in the ventral tegmental area is associated with the mesolimbic pathway. This pathway is critical for expression of conditioned place preferences, involved in motivation to undertake behaviors vital for survival, and implicated in addictive behaviors. It arises predominantly from the dorsal sheet of the SNc and dorsal VTA, innervating areas such as the amygdala and the nucleus accumbens, playing a major role in the limbic-motor integration.

The mesolimbic pathway is heavily implicated in the mechanisms of rewards and addiction, with dopamine acting as a critical neurotransmitter for these processes. Activation of this pathway increases the motivational drive ("wanting") for certain stimuli without necessarily increasing the hedonic pleasure ("liking"), explaining the compulsive nature of addictive behaviors.

Therefore, the correct answer to the question 'Dopamine in ventral tegmental area is associated with what pathway' is A) Mesolimbic pathway.