Answer :
Final answer:
The correct answer is option (b) 25 milligrams per dosage unit. The correct concentration limit for dihydrocodeine C-III is 25 milligrams per dosage unit, balancing efficacy and safety amid concerns of abuse and adverse effects.
Explanation:
Dihydrocodeine is an opioid medication that is regulated due to its potential for abuse and risk of accidental overdose. In formulations, dihydrocodeine concentrations are carefully controlled. The Federal Drug Administration (FDA) considers the safe and effective concentration for controlled substances like dihydrocodeine when used in medications. As dihydrocodeine is less potent than morphine but has a significant risk profile, especially in children, dosage units are kept to a limit that balances efficacy with safety. Therefore, the concentration limits for dihydrocodeine are not as high as 250 or 2,500 milligrams per dosage unit, which would be quite large and carry a high risk of adverse effects and potential for abuse.
Dihydrocodeine C-III concentration limit refers to the maximum amount of dihydrocodeine, a controlled substance, that can be present in a single dosage unit. The concentration limit is given in milligrams per dosage unit.
