Answer :
Final answer:
To calculate the dosage of Trimethoprim/sulfamethoxazole for a child weighing 15kg, you first compute the total daily dosage needed, then divide it by the number of times the medication is taken each day. After calculating how much active component contains 1 mL, dividing the dosage in mg by amount of medication in 1 mL will give us the dosage in mL.
Explanation:
First, let's calculate the total daily dosage for the child by multiplying the child's weight by the recommended dosage. So, it's 15 kg * 8 mg/kg/day = 120 mg/day. The Trimethoprim/sulfamethoxazole is dosed every 12 hours, so we need to divide the total daily dosage by 2 to get the dosage per 12 hours. That's 120 mg / 2 = 60 mg every 12 hours.
Now we know that the child should get 60 mg every 12 hours. To calculate the volume, we'll need to know the concentration of the medicine. Trimethoprim/sulfamethoxazole available in 200/40 mg/5 mL form - it means that there are 240 mg of active components in every 5 mL. It means that 1 mL contains 240/5 = 48 mg of the medication.
Hence, the dosage in mL is 60 mg * (1 mL / 48 mg) = 1.25 mL every 12 hours.
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