College

Calcium channel blockers can lead to peripheral edema as an adverse effect. Which of the following medications is known to cause peripheral edema due to calcium channel blockade?

a) Beta blockers
b) ACE inhibitors
c) Diuretics
d) Amlodipine

Answer :

Final answer:

Amlodipine is the medication known to cause peripheral edema due to its role as a calcium channel blocker, which differs from the mechanisms of beta blockers, ACE inhibitors, and diuretics.

Explanation:

Peripheral Edema and Calcium Channel Blockers

Among the medications listed, amlodipine is known to cause peripheral edema due to its mechanism as a calcium channel blocker. Unlike beta blockers, ACE inhibitors, and diuretics, amlodipine works by inhibiting the influx of calcium ions through channels in the vascular smooth muscle, leading to vasodilation and potentially causing edema. Other examples of calcium channel blockers include diltiazem, felodipine, nifedipine, nimodipine, nisoldipine, and verapamil, all of which can have similar side effects.