High School

By binding to smoothened and hindering the SHH pathway, what effect does it have?

1) Activating the SHH pathway
2) Inhibiting the SHH pathway
3) Enhancing the SHH pathway
4) Neutralizing the SHH pathway

Answer :

Final answer:

Binding to smoothened results in inhibition of the Sonic Hedgehog (SHH) pathway. This binding can initiate a series of intracellular events and significantly affect several downstream processes, ultimately leading to changes in body functions.

Explanation:

The question is asking about the effect of binding to smoothened and impeding the SHH pathway. This process mainly results in inhibiting the Sonic Hedgehog (SHH) pathway. The SHH pathway is a crucial signaling cascade that controls and regulates cell division and differentiation primarily during embryonic development.

The action of binding to 'smoothened' refers to the binding of a signaling molecule to a specific receptor protein. This binding can initiate a sequence of intracellular events that effectively slow down or hinder the efficiency of the pathway, categorizing this as inhibiting the SHH pathway.

The inhibition can alter several downstream events, such as gene transcription, protein synthesis, the activation/deactivation of enzymes, and other cellular responses, thereby significantly affecting body processes. Therefore, a single alteration in this signaling pathway can have multiple impacts depending on the interplay between two or more signaling pathways and the conditions within the cell.

Learn more about Inhibition of SHH pathway here:

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