Answer :
According to the mutation analysis of the GAL80 and GAL3 genes, GAL80 promotes GAL gene expression, and GAL3 inhibits GAL gene expression. Therefore, option c is correct.
The GAL genes are a set of genes in yeast cells that code for the proteins required to utilize galactose as a carbon source for cellular metabolism. The expression of the GAL genes is regulated by the interaction of different transcription factors with the GAL gene promoters.Two of these transcription factors are GAL80 and GAL3. GAL80 is a repressor that binds to the DNA and inhibits GAL gene expression. In contrast, GAL3 is an activator that binds to GAL80 and relieves its inhibitory effect on the gene expression.
Mutations in the GAL80 and GAL3 genes have been studied to understand the roles of these factors in regulating the expression of the GAL genes. The results show that the GAL80 mutations prevent the protein from binding to DNA, which leads to an increase in the GAL gene expression. In contrast, mutations in the GAL3 gene prevent the protein from binding to GAL80, which leads to an inhibition of GAL gene expression.Thus, the correct answer to the question is option c: GAL80 promotes GAL gene expression, and GAL3 inhibits GAL gene expression.
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