Answer :
Final answer:
Alzheimer's disease is characterized by a deficiency in the transmission of the neurotransmitter acetylcholine, caused by a decrease in the activity of cholinergic neurons. Treatments often work by increasing acetylcholine neurotransmission. Beta-amyloid plaques in the brain are also associated with the disease.
Explanation:
Alzheimer's disease, a neurodegenerative disease, is characterized by the decline in the activity of cholinergic neurons. These neurons use a neurotransmitter called acetylcholine. A common symptom of Alzheimer's is a deficiency in the neurotransmission of acetylcholine. Many drugs designed to treat Alzheimer's function by increasing the acetylcholine neurotransmission. This is often done by inhibiting the enzyme that decomposes acetylcholine in the synaptic cleft. Apart from acetylcholine, Alzheimer's disease is also associated with a protein called beta-amyloid. This protein, when not functioning correctly, forms plaques in the brain, contributing to the neurodegeneration seen in Alzheimer's patients.
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