According to USP NF/797, what is the requirement for carts when crossing over clean zones in a clean room?

1. Carts must be cleaned and sanitized before crossing over clean zones.
2. Carts can cross over clean zones without any cleaning or sanitization.
3. Carts must be cleaned and sanitized after crossing over clean zones.
4. Carts are not allowed to cross over clean zones in a clean room.

USP NF/797 requires carts to be cleaned and sanitized before crossing over clean zones in a clean room to minimize the risk of contamination and maintain sterile conditions. Therefore, the correct answer is option 1.

Explanation:

According to the USP NF/797, carts must be cleaned and sanitized before crossing over clean zones in a clean room. Therefore, the correct answer is option 1.

This requirement is essential to maintain the sterile conditions within these zones by minimizing the risk of contamination. The USP NF/797 guidelines are designed to ensure the safe compounding of pharmaceutical products by laying down stringent protocols for cleanliness and sanitation within pharmaceutical compounding facilities, including how equipment such as carts are handled when crossing between different cleanliness zones within a clean room.