Answer :
Final answer:
In a situation of cardiac arrest and ventricular fibrillation refractory to shocks, the first drug choice is Epinephrine 1 mg, which boosts blood pressure, improves coronary perfusion and increases cardiac contractions. So the correct option is 1. Epinephrine 1 mg.
Explanation:
In the context of cardiac arrest and ventricular fibrillation that is refractory to shocks, the first-line drug of choice, according to Advanced Cardiovascular Life Support (ACLS) guidelines, is 1. Epinephrine 1 mg administered IV/IO.
Epinephrine acts to stimulate alpha-1 adrenergic receptors, causing increased peripheral vascular resistance and subsequently increased arterial blood pressure and coronary perfusion pressure. It also stimulates beta-1 adrenergic receptors, improving the force of cardiac contractions.
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