A drug comes at a concentration of 0.50 mg/ml. If a patient is dosed at 12 mcg/kg/min, calculate the required rate of infusion for this solution in ml/hr for a patient that weighs 103 kg.

To calculate the required rate of infusion, you first convert the given dosage to match the units, multiply this by the patient's weight to get the total required dosage per hour, and then divide this by the drug's concentration to find the volume of drug to be infused per hour. The calculated infusion rate for a 103 kg patient would be 148 ml/hr.

Explanation:

The required rate of infusion can be calculated in a few steps. First, convert the dosage to the same units, so 12 mcg/kg/min is equivalent to 720 mcg/kg/hr (since there are 60 minutes in an hour). Multiply this by the patient's weight to get the total dosage required per hour, which is 73,920 mcg/hr (or 74 mg/hr) for a 103 kg patient. Now, as the drug concentration is 0.50 mg/ml, the volume of the drug to be infused per hour is calculated by dividing the total dosage required per hour by the concentration of the drug. Therefore, the infusion rate required is 148 ml/hr.

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