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A certain drug must be given as 100 mg per day. Which of the following factors affect the drug's plasma concentration at steady state:

a) How many doses of these 100 mg medicines are distributed over (ie if you take 100 mg once/24 hours or 50 mg twice/24 hours)

b) The drug's clearance

c) Whether a shock dose has been given or not

d) If the drug is taken orally or intravenously

Answer :

Sedate plasma concentration at an unfaltering state is impacted by dosing recurrence, clearance rate, and course of organization, whereas stun dosages affect introductory levels.

Which of the following factors affect the drug's plasma concentration at steady state?

The plasma concentration of a medication at a consistent state is impacted by a few variables:

a) Dose Recurrence: The recurrence of medicate organization influences plasma concentration. Part a 100 mg measurements into two 50 mg dosages comes about in lower crest levels and possibly more steady concentrations compared to a single day-by-day 100 mg dosage.

b) Sedate Clearance: Clearance alludes to the rate at which a medicate is evacuated from the body. Higher clearance leads to speedier disposal, possibly requiring bigger or more visit measurements to preserve a relentless state concentration.

c) Stun Measurements: A stun dosage or stacking dosage can incidentally hoist sedate levels to reach helpful concentrations rapidly. In any case, it doesn't influence steady-state concentration, as it's taken after normal support measurements.

d) Course of Organization: The course can impact retention and bioavailability. Intravenous organization frequently comes about in quick, exact medicate conveyance and higher introductory concentrations compared to verbal courses.

In rundown, dosing recurrence, clearance, and course of organization altogether affect a drug's plasma concentration at a relentless state. Stun measurements essentially impact introductory levels and aren't a long-term figure.

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