College

8. Receptors of insulin are:
- A. Tyrosine kinase receptors
- B. GABA receptors
- C. G-protein coupled receptor
- D. No answer is correct

9. The most common complication in insulin therapy is:
- A. Lipodystrophy
- B. Hypotension
- C. Hypoglycemia
- D. Gallstone

10. The duration of barbiturate action mainly depends on:
- A. Rate of hepatic metabolism
- B. Excretion rate from renal and/or pulmonary systems
- C. Lipid solubility and time to distribute throughout the body
- D. Pharmacogenetic differences between patients

11. What is the advantage of metformin over sulfonylureas in the management of type 2 diabetes?
- A. It does not cause hypoglycemia
- B. It increases insulin release from the pancreas B cells
- C. It can also be indicated for fertility
- D. It causes weight gain

12. A common adverse reaction to misoprostol is:
- A. Indigestion
- B. Constipation
- C. Headache
- D. Diarrhea

13. How does simethicone relieve gas in the GI tract?
- A. It disperses and prevents gas pocket formation.
- B. It facilitates expulsion of gas pockets.
- C. It neutralizes gastric contents and reduces gas.
- D. It coats and protects the lining of the stomach.

14. The antiemetic drug that would probably be best for a patient experiencing motion sickness on an airplane is:
- A. Chlorpromazine
- B. Haloperidol
- C. Dimenhydrinate
- D. Dolasetron

15. What is true of acid control therapy with H2 blockers:
- A. It generally heals duodenal ulcers faster than gastric ulcers
- B. It checks bleeding in case of a bleeding peptic ulcer
- C. It prevents gastroesophageal reflux
- D. Both 'A' and 'B' are correct

Answer :

Final answer:

Insulin receptors are primarily Tyrosine Kinase receptors, and the most common complication of insulin therapy is hypoglycemia. Barbiturate action duration is mainly determined by hepatic metabolism, while metformin offers the advantage of not causing hypoglycemia. Additionally, simethicone relieves gas by facilitating expulsion of gas pockets, and dimenhydrinate is best for motion sickness, while H2 blockers aid in managing bleeding peptic ulcers.


Explanation:

Receptors of Insulin

The receptors for insulin are primarily Tyrosine Kinase receptors (Answer A). These receptors play a crucial role in cell signaling and are a type of receptor that phosphorylates tyrosine residues on target proteins, leading to various metabolic actions such as glucose uptake in cells.

Common Complication in Insulin Therapy

The most common complication of insulin therapy is Hypoglycemia (Answer C). This occurs when blood glucose levels fall too low, which can happen due to various factors such as administering too much insulin or not eating enough carbohydrates.

Duration of Barbiturate Action

The duration of action of barbiturates mainly depends on their rate of hepatic metabolism (Answer A). This means how quickly the liver can metabolize or break down barbiturates affects how long their effects last in the body.

Advantage of Metformin

One significant advantage of metformin over sulfonylureas in managing type 2 diabetes is that it does not cause hypoglycemia (Answer A). Unlike sulfonylureas, which can lead to increased insulin secretion and subsequent hypoglycemia, metformin primarily decreases hepatic glucose production.

Common Adverse Reaction to Misoprostol

A common adverse reaction to misoprostol is Diarrhea (Answer D). This is a frequent side effect because misoprostol stimulates the production of gastric mucus and bicarbonate, which can lead to gastrointestinal disturbances.

Relief of Gas in the GI Tract

Simethicone relieves gas in the GI tract because it facilitates the expulsion of gas pockets (Answer B). It works by decreasing the surface tension of gas bubbles, allowing them to merge and become easier to expel.

Best Antiemetic for Motion Sickness

The best antiemetic drug for a patient experiencing motion sickness on an airplane is Dimenhydrinate (Answer C). Dimenhydrinate is an antihistamine that effectively prevents nausea and vomiting associated with motion sickness.

Acid Control Therapy with H2 Blockers

In acid control therapy with H2 blockers, it checks bleeding in case of bleeding peptic ulcer (Answer B). H2 blockers reduce stomach acid secretion, helping to promote healing of ulcers and control bleeding.


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