When a B cell is shown an antigen on a class II major histocompatibility complex (MHC) protein, it will go through _ and B cells subsequently can and/or _ _____.

A) Clonal expansion; differentiate into plasma cells; memory cells
B) Clonal selection; produce antibodies; undergo apoptosis
C) Antibody production; undergo an allergic reaction; phagocytose pathogens
D) Apoptosis; undergo clonal expansion; activate T cells

Option (A), When a B cell interacts with an antigen presented on MHC II, it undergoes clonal expansion resulting in the differentiation into plasma cells that produce antibodies, and memory B cells that enhance future immune responses.

Explanation:

When a B cell is shown an antigen on a class II major histocompatibility complex (MHC) protein, it will go through clonal expansion and B cells subsequently can differentiate into plasma cells and/or memory cells.

The correct option is A) Clonal expansion; differentiate into plasma cells; memory cells.

After the B cell receptor (BCR) binds to an antigen, the B cell internalizes the antigen and presents it on MHC II. A helper T cell recognizes this complex and activates the B cell.

Then, both plasma cells and memory B cells are generated.

Plasma cells are responsible for secreting antibodies, while memory B cells are crucial for a quicker response upon future encounters with the same antigen, conferring immunological memory.